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Zenegra 50 mg is a medication used to treat erectile dysfunction (ED) in men. It contains sildenafil citrate as its active ingredient, which is a phosphodiesterase type 5 (PDE5) inhibitor. The effects of Zenegra 50 mg typically last for about 4 to 6 hours. Sexual stimulation is necessary for the medication to be effective. Zenegra 50 mg should not be taken with certain medications, especially those containing nitrates.