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Zhewitra 20 mg is a medication used to treat erectile dysfunction (ED) in men. It contains vardenafil as its active ingredient, which belongs to a class of medications called phosphodiesterase type 5 (PDE5) inhibitors. Vardenafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. By inhibiting PDE5, vardenafil helps to enhance the effects of nitric oxide, leading to relaxation of the smooth muscle cells and increased blood flow to the penis during sexual stimulation.