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Malegra DXT combines the benefits of both sildenafil and duloxetine in a single medication, providing a dual-action approach to address both ED and PE. The dosage and usage instructions for Malegra DXT should be followed as prescribed by a healthcare professional. It is typically taken orally with water. Like any medication, Malegra DXT can have side effects. Common side effects may include headaches, dizziness, flushing, indigestion, and changes in vision. If you experience severe or persistent side effects, consult your healthcare provider.