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Sildalist is a combination medication that contains two active ingredients: sildenafil citrate and tadalafil. Both sildenafil and tadalafil are phosphodiesterase type 5 (PDE-5) inhibitors used to treat erectile dysfunction (ED) in men. This is the same active ingredient found in Viagra. Sildenafil is a PDE-5 inhibitor that works by increasing blood flow to the penis during sexual stimulation, facilitating the ability to achieve and maintain an erection.