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Before using Vidalista 5 or any medication for ED, it's important to consult with a healthcare professional. They can assess your health, discuss potential side effects, and determine if Vidalista 5 is a suitable and safe option for you. The onset of action for tadalafil is typically about 30 minutes to an hour before sexual activity. Tadalafil has a relatively longer duration of action compared to some other PDE5 inhibitors, and its effects can last for up to 36 hours.