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Suhagra 100 response is mediated with the aid of the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP reasons smooth muscle relaxation and elevated blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type five (PDE5) by way of sildenafil complements erectile feature through increasing the amount of cGMP.
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