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Kamagra Oral Jelly contains sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor. Sildenafil Sildenafil in Kamagra Oral Jelly acts on the erectile tissue of the penis to increase blood flow into the penis, which is needed to cause an erection. During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase.