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Vidalista 60 works similarly to other tadalafil-based medications by inhibiting the phosphodiesterase type 5 (PDE5) enzyme. This enzyme typically breaks down cyclic guanosine monophosphate (cGMP), a compound that helps relax smooth muscle tissue and dilate blood vessels. By preventing the breakdown of cGMP, Vidalista 60 increases blood flow to the penis, which aids in achieving and maintaining an erection.