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Cenforce 100 mg is a commonly prescribed dose for ED. The usual starting dose is 50 mg, but it can be increased to 100 mg based on effectiveness and tolerability. The maximum recommended dose is 100 mg per day. Sildenafil citrate in Cenforce 100 mg inhibits the enzyme phosphodiesterase type 5 (PDE5). This leads to increased levels of cyclic guanosine monophosphate (cGMP), which causes relaxation of the smooth muscles in the blood vessels of the penis.