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While Tadarise 40 mg is generally safe and well-tolerated, it's essential to follow the prescribed dosage and instructions. Avoiding alcohol, grapefruit juice, and certain medications that may interact with tadalafil can help prevent potential side effects and ensure optimal results. Before using Tadarise 40 mg or any similar medication for ED, it's important to consult with a healthcare provider. They can evaluate your medical history, current medications, and overall health to determine if Tadarise is suitable for you.