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Megalis 20 mg is a medication that contains tadalafil, used primarily for the treatment of erectile dysfunction (ED) and sometimes for benign prostatic hyperplasia (BPH). Here’s what you should know about Megalis 20 mg: Indications Erectile Dysfunction (ED): Helps men achieve and maintain an erection when sexually stimulated. Benign Prostatic Hyperplasia May help relieve symptoms associated with enlarged prostate.