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Though Tadalista 20 offers various benefits, certain individuals should exercise caution when using this medication. Patients with severe heart disease, particularly those who are not stable or who have recently experienced a heart attack or stroke, should avoid Tadalafil without a thorough evaluation from a healthcare provider. Moreover, Tadalista 20 can interact negatively with certain cardiovascular medications, particularly nitrates. The combination of these medications can lead to dangerously low blood pressure. It’s essential for patients to discuss their full medical history and current medications with their healthcare provider to ensure Tadalista 20 is safe for them.