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Tadarise 10 mg contains tadalafil, which inhibits the enzyme phosphodiesterase type 5 (PDE5). This inhibition leads to increased levels of cyclic guanosine monophosphate (cGMP). Elevated cGMP levels cause relaxation of the smooth muscles and dilation of the blood vessels in the penis, resulting in improved blood flow and the ability to achieve and maintain an erection in response to sexual stimulation.