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Alzheimer's disease is a neurodegenerative disorder marked by the accumulation of beta-amyloid plaques and neurofibrillary tangles in the brain, leading to neuronal death and cognitive impairment. Neurovascular coupling refers to the tight relationship between neural activity and cerebral blood flow. In healthy individuals, increased neuronal activity triggers vasodilation of nearby blood vessels, ensuring a steady supply of oxygen and glucose to meet metabolic demands.